0 Completely Explosive Autonomous High-Voltage Pulsed-Power System Based on Shockwave Ferromagnetic Primary Power Source and Spiral Vector Inversion Generator

Title	:	Completely Explosive Autonomous High-Voltage Pulsed-Power System Based on Shockwave Ferromagnetic Primary Power Source and Spiral Vector Inversion Generator
Authors	:	Sergey I. Shkuratov, Evgueni F. Talantsev, Jason Baird, Millard F. Rose, Zachary Shotts, Zack Roberts, Larry L. Altgilbers, Allen H. Stults
		IEEE TRANSACTIONS ON PLASMA SCIENCE, VOL. 34, NO. 5, OCTOBER 2006

Abstract

Novel explosive and conventional pulsed-power technologies were combined, and a series of explosive-driven high–voltage power supplies was designed, built, and tested. The power supply contained an explosive-driven high-voltage primary power source based on the fundamental physical effect of shockwave demagnetization of Nd2Fe14B high-energy ferromagnet and a power-conditioning stage. The volume of the energy-carrying ferromagnetic elements in the shockwave ferromagnetic generators (FMGs) was 8.75 cm3. The power-conditioning stage was based on the spiral vector inversion generator (VIG). The combined FMG–VIG system demonstrated successful operation and good performance. The output-voltage pulse amplitude of the combined FMG–VIG system exceeded 40 kV, with a rise time of 6.2 ns. The methodology was developed for digital simulation of the operation of completely explosive FMG–VIG system. Experimental results obtained are in a good agreement with the results of digital calculations performed.

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0 Physical Modeling of Magneto Hydrodynamic Explosive Munition and Detonation Control

Title	:	Physical Modeling of Magneto Hydrodynamic Explosive Munition and Detonation Control
Authors	:	Yun Lei Shi, Shao Jie Ma, He Zhang, Lin Gu
		Applied Mechanics and Materials Vols 300-301 (2013) pp 1448-1453

Abstract

Definition of magneto hydrodynamic explosive munition is introduced. The technology that magneto hydrodynamic loaded EFP is presented. The magneto hydrodynamic power is generated by MFCG. The physical model of magneto hydrodynamic explosive munition using ferroelectric ceramics as primary source is established. The equivalent circuit of primary source, MFCG and magneto hydrodynamic accelerating model is analyzed by current transfer process. The security system is designed for the new ammunition, and its initiation timing is analyzed. A microsecond detonation control method is also given.

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0 Advances in Planar Lipid Bilayers and Liposomes, Volume 13 [Ales Iglic, 2011]

Title	:	Advances in Planar Lipid Bilayers and Liposomes, Volume 13
Editor	:	Ales Iglic

Advances in Planar Lipid Bilayers and Liposomes volumes cover a broad range of topics, including main arrangements of the reconstituted system, namely planar lipid bilayers as well as spherical liposomes. The invited authors present the latest results of their own research groups in this exciting multidisciplinary field.

• Incorporates contributions from newcomers and established and experienced researchers
• Explores the planar lipid bilayer systems and spherical liposomes from both theoretical and experimental perspectives
• Serves as an indispensable source of information for new scientists

PDF: Advances in Planar Lipid Bilayers and Liposomes, Volume 13 [Ales Iglic, 2011]

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0 A dictionary of behavioral motifs reveals clusters of genes affecting Caenorhabditis elegans locomotion

Title	:	A dictionary of behavioral motifs reveals clusters of genes affecting Caenorhabditis elegans locomotion
Authors	:	André E X Brown, Eviatar I Yemini, Laura J Grundy, Tadas Jucikas, and William R Schafer

Visible phenotypes based on locomotion and posture have played a critical role in understanding the molecular basis of behavior and development in Caenorhabditis elegans and othermodel organisms. However, it is not known whether these human-defined features capture the most important aspects of behavior for phenotypic comparison or whether they are sufficient to discover new behaviors. Here we show that four basic shapes, or eigenworms, previously described for wild-type worms, also capture mutant shapes, and that this representation can be used to build a dictionary of repetitive behavioral motifs in an unbiased way. By measuring the distance between each individual’s behavior and the elements in the motif dictionary,wecreate a fingerprint that can be used to compare mutants to wild type and to each other. This analysis has revealed phenotypes not previously detected by real-time observation and has allowed clustering of mutants into related groups. Behavioral motifs provide a compact and intuitive representation of behavioral phenotypes.

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0 A conserved NAD+ binding pocket that regulates protein-protein interactions during aging

Title	:	A conserved NAD+ binding pocket that regulates protein-protein interactions during aging
Authors	:	Jun Li, Michael S Bonkowski, Sébastien Moniot, Dapeng Zhang, Basil P Hubbard, Alvin J Y Ling, Luis A Rajman, Bo Qin, Zhenkun Lou, Vera Gorbunova, L Aravind, Clemens Steegborn, David A Sinclair

DNA repair is essential for life, yet its efficiency declines with age for reasons that are
unclear. Numerous proteins possess Nudix homology domains (NHDs) that have no
known function. We show that NHDs are NAD+ (oxidized form of nicotinamide adenine
dinucleotide) binding domains that regulate protein-protein interactions. The binding
of NAD+ to the NHD domain of DBC1 (deleted in breast cancer 1) prevents it from
inhibiting PARP1 [poly(adenosine diphosphate–ribose) polymerase], a critical DNA repair
protein. As mice age and NAD+ concentrations decline, DBC1 is increasingly bound to
PARP1, causing DNA damage to accumulate, a process rapidly reversed by restoring the
abundance of NAD+. Thus, NAD+ directly regulates protein-protein interactions, the
modulation of which may protect against cancer, radiation, and aging.

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